3-Substituted Furans.
نویسندگان
چکیده
منابع مشابه
Pd/Cu-catalyzed cascade Sonogashira coupling/cyclization reactions to highly substituted 3-formyl furans.
An efficient palladium/copper-catalyzed approach to the synthesis of highly substituted 3-formyl furans from the reactions of readily available α-bromoenaminones with terminal alkynes has been developed. This methodology was realized by the cascade reactions of Sonogashira coupling and the subsequent intramolecular cyclization.
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The normal urinary chromatographic pattern on the high-resolution UV-Analyzer exhibits approximately 20 major peaks and more than 100 minor peaks. Three of the major chromatographic peaks, observed in most urinary samples from both normal and pathologicsubjects,have recentlybeen identified as 5.hydroxymethyl.2furoic acid, 2-furoylglycine, and 2,5-furand ica rboxylic acid. A related compound, 5....
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An efficient protocol was developed to access 3-fluoro-2-hydroxy-2-substituted benzo[b]furans with Selectfluor™ as the fluorinating reagent in MeCN and water. By utilizing SOCl2/Py as the dehydrating agent, the compounds above were readily converted to 3-fluorinated, 2-substituted benzo[b]furans in high yields.
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The olefin cross-metathesis (CM) reaction is used extensively in organic chemistry and represents a powerful method for the selective synthesis of differentially substituted alkene products. Surprisingly, efforts to integrate this remarkable process into strategies for aromatic and heteroaromatic construction have not been reported. Such structures represent key elements of the majority of smal...
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transforming relatively complex starting materials into substituted heterocycles, and for the functionalization of existing heterocycles, there is less precedent for methodology which involves the direct, regiodefined synthesis of highly substituted heterocycles from simple starting materials. As such, new methods for the synthesis of substituted heterocycles (or their precursors) are potential...
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ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1961
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.15-1419